Relationship between the Blood Pressure and Serum Uric Acid Levels in Pregnant Women

Abstract

Introduction and Objectives

Exploring the intricate interplay of serum uric acid and blood pressure offers critical insights into pregnancy- related hypertensive disorders. This study was conducted to determine whether if there is a statistically

significant correlation between blood pressure and serum uric acid levels in pregnant women. Methods All the selected subjects were included and there were no dropouts. Study showed a significant positive correlation between serum uric acid levels with both systolic (r=0.864, p<0.001) and diastolic (r=0.739, p<0.001) blood pressures. In addition, statistically significant (p<0.001) positive correlation was observed between serum uric acid levels and systolic blood pressure among those with different body mass index (BMI) categories (underweight; r=0.955, normal; r=0.910, overweight; r=0.817, obesity; r=0.721) and gestational weeks (trimester) (second; r=0.780, third; r=0.878). Meanwhile, similar statistically significant (p<0.001) positive correlations between serum uric acid levels and diastolic blood pressure among different BMI categories (underweight; r=0.867, normal; r=0.625, overweight; r=0.772, obesity; r=0.650) and gestational weeks (trimester) (second; r=0.809, third; r=0.730) were observed. Conclusions Robust and significant positive correlations between serum uric acid with both systolic and diastolic blood pressures were observed. This suggests that uric acid can be used as a predictor of hypertensive disorders of pregnancy like pre-eclampsia in a wide range of pregnant women regardless of their characteristics like BMI and gestational period.