Traceless solid phase synthesis of 2-substituted pyrimidines using an 'off-the-shelf' chlorogermane-functionalised resin
| dc.contributor.author | Spivey, A.C. | |
| dc.contributor.author | Srikaran, R. | |
| dc.contributor.author | Diaper, C.M. | |
| dc.contributor.author | Turner, D.J. | |
| dc.date.accessioned | 2014-02-05T18:00:17Z | |
| dc.date.accessioned | 2022-07-11T08:25:13Z | |
| dc.date.available | 2014-02-05T18:00:17Z | |
| dc.date.available | 2022-07-11T08:25:13Z | |
| dc.date.issued | 2003-05 | |
| dc.description.abstract | The parallel solid phase synthesis of an 18-member library of 2-substituted pyrimidines is described using a chlorogermane-functionalised resin. The success of the key Pinner-type condensations between a resin-bound enaminone and an array of amidine hydrochlorides highlights the stability of arylgermane linkers (cf. arylsilanes) towards strongly basic/nucleophilic conditions. | en_US |
| dc.identifier.issn | 14770520 | |
| dc.identifier.uri | http://repo.lib.jfn.ac.lk/ujrr/handle/123456789/246 | |
| dc.language.iso | en | en_US |
| dc.title | Traceless solid phase synthesis of 2-substituted pyrimidines using an 'off-the-shelf' chlorogermane-functionalised resin | en_US |
| dc.type | Article | en_US |